Healthcare Supplement
Bifidobacterium Adolescentis Powder
Bifidobacterium Adolescentis Powder Manufacturers
Kintainutri® Extracts supplies high-activity, high-purity bifidobacterium adolescentis powder raw materials, featuring an effective viable cell count ranging from 1.0 × 10¹⁰ to 5.0 × 10¹¹ CFU/g. Bifidobacterium adolescentis is a Gram-positive, anaerobic, and non-spore-forming intestinal probiotic that primarily colonizes the intestines of healthy individuals aged 16 to 45, as well as centenarians; it is closely associated with host longevity and intestinal homeostasis. This bacterial strain exhibits a strong ability to ferment complex carbohydrates, including resistant starch, cellulose, and pectin, thereby producing acetic acid, lactic acid, and short-chain fatty acids (SCFAs) while simultaneously synthesizing B-group vitamins such as folic acid.
Furthermore, Bifidobacterium adolescentis serves as a primary producer of gamma-aminobutyric acid (GABA) within the human gut, demonstrating unique potential in the regulation of the gut-brain axis. It is ideally suited for the development of functional foods, dietary supplements, and microbial ecological preparations. Should you require further details, we invite you to contact us for a consultation.
| Item | Specification | Test result |
|---|---|---|
| Physical Control | ||
| Appearance | White powder | Visual |
| Odor | Characteristic | Organoleptic |
| Taste | Characteristic | Organoleptic |
| Content | 10 billion CFU/G | AOAC |
| Loss on Drying | ≤5.0% | USP <731> / 105℃, 3h |
| Ash | ≤5.0% | USP <561> / 550℃ |
| Particle size | 95% pass 80 mesh | USP <786> |
| Allergens | None | ELISA |
| Chemical Control | ||
| Heavy metals | NMT 10ppm | ICP-MS |
| Arsenic | NMT 2ppm | ICP-MS |
| Lead | NMT 2ppm | ICP-MS |
| Cadmium | NMT 2ppm | ICP-MS |
| Mercury | NMT 2ppm | ICP-MS |
| GMO Status | GMO Free | PCR |
| Microbiological Control | ||
| Total Plate Count | 10,000cfu/g Max | AOAC |
| Yeast & Mold | 1,000cfu/g Max | AOAC |
| E.Coli | Negative | AOAC |
| Salmonella | Negative | AOAC |
How To Make Bifidobacterium Adolescentis Powder?
Bifidobacterium Adolescentis Powder Benefits
Regulating Gut Health
Bifidobacterium adolescentis enhances intestinal barrier function through multiple mechanisms. First, it metabolizes substrates to produce short-chain fatty acids (SCFAs), thereby increasing the thickness of the intestinal mucus layer. Second, it significantly upregulates the expression of tight junction proteins, specifically ZO-1, Occludin, and Claudin-2, thereby reducing intestinal permeability and preventing bacterial translocation as well as the entry of endotoxins into the bloodstream. Third, it maintains intestinal microbial balance by competitively inhibiting the growth of harmful bacteria, such as Salmonella and Staphylococcus aureus.
Notably, the abundance of this bacterium is significantly reduced in patients suffering from intestinal disorders such as IBD and IBS. Kintainutri®’s Bifidobacterium adolescentis powder serves as a high-quality probiotic ingredient suitable for use in functional foods and specialized medical formulas.
Enhancing Immune and Anti-inflammatory Functions
Bifidobacterium adolescentis powder Bif-94 activates the TLR2 signaling pathway via the peptidoglycan (PG) components within its cell wall, thereby promoting the production of the anti-inflammatory cytokine IL-10 by regulatory B cells (Bregs). This mechanism effectively alleviates DSS-induced colitis in mice. Compared to the reference strain, this specific strain upregulates the expression of several genes associated with peptidoglycan synthesis (such as MurE, MurD, Alr, and UppP), resulting in enhanced PG production. In human colonic B cells, both Bif-94 and its associated peptidoglycans have been shown to induce IL-10 secretion.Our Bifidobacterium adolescentis powder is suitable for use as a raw material in the development of functional foods and specialized medical foods targeting inflammatory bowel disease, immune modulation, and related applications.
Improving Mental State
Bifidobacterium adolescentis is a "mood-regulating bacterium" that naturally resides in the human gut. Through the action of glutamate decarboxylase (GAD), it converts dietary glutamate into gamma-aminobutyric acid (GABA), which serves as the body's primary inhibitory neurotransmitter and helps to alleviate symptoms of anxiety and depression. Studies have revealed that children exhibiting symptoms of anxiety possess significantly higher abundances of B. adolescentis and its associated GABA-synthesis genes within their gut microbiota. Furthermore, animal studies have confirmed that supplementation with specific strains of B. adolescentis (such as PRL2019 and HD17T2H) can elevate endogenous GABA levels. Consequently, this bacterium is well-suited for use as a functional food ingredient aimed at promoting emotional well-being, aiding sleep, and reducing stress.
What Is Bifidobacterium Adolescentis Powder Used For？
In the healthcare sector
Bifidobacterium adolescentis has been developed into probiotic preparations and dietary supplements. It is primarily utilized in the treatment of digestive disorders, such as antibiotic-associated diarrhea, chronic diarrhea, functional constipation, and irritable bowel syndrome (IBS), exerting its therapeutic effects by regulating intestinal microbiota balance and repairing the intestinal barrier. Furthermore, it has demonstrated promising potential as an adjunctive therapy for metabolic disorders, including Type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and metabolic syndrome. Additionally, this bacterial strain aids in boosting immunity and preventing respiratory and gastrointestinal infections; it is particularly beneficial for the elderly and individuals with compromised immune systems, serving as a premium ingredient for functional foods and specialized medical formulas.
In the food industry
Bifidobacterium adolescentis is widely utilized in the development of functional foods, thanks to its exceptional probiotic properties. It serves a dual role, acting as a starter culture in the production of dairy products such as yogurt, fermented milk beverages, and cheese, while also being incorporated into products such as probiotic powders and functional beverages. By consuming foods containing this specific strain, consumers can help replenish beneficial intestinal flora, maintain the balance of their gut microbiota, and promote overall digestive health.
Safety Of Bifidobacterium Adolescentis Powder
Bifidobacterium adolescentis powder demonstrates a favorable safety profile at standard dosages; product labeling typically notes that "no adverse reactions have been observed." Animal studies have confirmed that it exhibits no toxicity to the liver or kidneys. A small subset of sensitive individuals may experience transient gastrointestinal reactions, including mild abdominal bloating or increased flatulence, upon initial intake; these symptoms typically resolve spontaneously.
However, caution is advised for individuals with compromised immune systems (e.g., patients undergoing chemotherapy or organ transplantation), critically ill patients, and those with known allergies to the product's ingredients. Overall, this bacterial strain possesses a high safety margin as a probiotic ingredient, making it suitable for the development of functional foods and dietary supplements intended for the general population.
Kintainutri® Bifidobacterium Adolescentis Powder Advantages
Kintainutri® is a manufacturer of bifidobacterium adolescentis powder, offering a comprehensive technical documentation package (including COAs, TDSs, MSDSs, and allergen-free and non-GMO statements). We provide customized solutions for viable cell counts and ingredient blending. From formula development to regulatory registration, we supply stable, compliant, and highly active core ingredients for your adult dietary supplements, functional foods, and innovative skincare lines. Choose Kintainutri® as your reliable and trusted partner and contact us today.
*Kintainutri® Promise All Products: Non-Irradiated / Non-ETO/ Treat by Heat Only / Non-GMO
FAQ
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